Inject RELISTOR subcutaneously in the upper arm, abdomen or thigh. Do not inject at the same spot each time (rotate injection sites). Once drawn into the 1 mL syringe with a 27-gauge x ½-inch needle, if immediate administration is not possible, store at ambient room temperature and administer within 24 hours.

How often can RELISTOR be given?

The recommended dosage of RELISTOR tablets is 450 mg taken orally once daily in the morning. The recommended dosage of RELISTOR injection is 12 mg administered subcutaneously once daily.

How do you take RELISTOR tablets?

RELISTOR tablets offer convenient once-daily dosing ¹

1. Take RELISTOR tablets with water on an empty stomach at least 30 minutes before the first meal of the day.
2. Discontinue all maintenance laxative therapy prior to initiation of RELISTOR.
3. RELISTOR therapy should be continued only during opioid use.

How long does it take RELISTOR to work?

It works by preventing opioid medications from binding to certain receptors in the intestinal tract. It does not reduce the pain-relieving effects of opioid pain medications. For most people, methylnaltrexone usually works within 30 minutes, but it may take longer.

Where do you inject Relistor?

Inject RELISTOR subcutaneously in the upper arm, abdomen or thigh. Do not inject at the same spot each time (rotate injection sites). Once drawn into the 1 mL syringe with a 27-gauge x ½-inch needle, if immediate administration is not possible, store at ambient room temperature and administer within 24 hours.

Can you take a laxative with Relistor?

If you’re using opioids for non-cancer-related pain, stop taking all laxatives before starting on Relistor ( methylnaltrexone ). You can start using laxatives again if you’re still constipated after using this medication for 3 days.

What drug class is Relistor?

Quaternary ammonium cation

What is the difference between relistor and Movantik?

When laxatives aren’t enough, Relistor (methylnaltrexone) can help treat constipation caused by opioids without affecting opioid pain relief. Relieves constipation caused by opioid pain relievers. Movantik (naloxegol) is a good option for treating constipation due to the use of opioids.

Can I take Relistor after I eat?

Food may reduce the absorption of methylnaltrexone when taken orally, which may lead to lower blood levels of the medication and possibly reduced effectiveness. You should take oral preparations of methylnaltrexone on an empty stomach at least 30 minutes before your first meal of the day.

How effective is Relistor?

Methylnaltrexone is a highly effective medicine. One 2016 study found that 45.9 percent of people taking methylnaltrexone experienced a rescue-free bowel movement within 4 hours of the first dose.

Is relistor over the counter?

Indications. RELISTOR^® is a prescription medicine used to treat constipation in adults that is caused by prescription pain medicines called opioids.

How can I make myself poop instantly?

The following quick treatments can help induce a bowel movement in a few hours.

1. Take a fiber supplement.
2. Eat a serving of high-fiber food.
3. Drink a glass of water.
4. Take a laxative stimulant.
5. Take an osmotic.
6. Try a lubricant laxative.
7. Use a stool softener.
8. Try an enema.

Does relistor cause withdrawal?

You may have symptoms of opioid withdrawal during treatment with RELISTOR including sweating, chills, diarrhea, stomach pain, anxiety, and yawning. Tell your healthcare provider if you have any of these symptoms.

How long is too long to be constipated?

Going longer than 3 or more days without one, though, is usually too long. After 3 days, your stool gets harder and more difficult to pass.