Intravenous Infusion: 4 g in 250 mL of 5% Dextrose Injection at a rate not exceeding 3 mL per minute. Usual Dose Range: 1 to 40 g daily. Electrolyte Replenisher: Intramuscular 1 to 2 g in 50% solution four times a day until serum magnesium is within normal limits.

How do you give magnesium IV?

To initiate therapy, 4 g of Magnesium Sulfate in Water for Injection may be administered intravenously. The rate of I.V. infusion should generally not exceed 150 mg/minute, or 3.75 mL of a 4% concentration (or its equivalent) per minute, except in severe eclampsia with seizures.

What is the protocol for magnesium sulphate?

Magnesium sulphate is recommended as the first -line medication for prophylaxis and treatment of eclampsia. The loading dose is 4 g IV over 20 to 30 min, followed by a maintenance dose of 1 g/h by continuous infusion for 24 h or until 24 h after delivery, whichever is later.

How do you prepare and administer magnesium sulfate?

Initiate magnesium sulfate with a loading dose (bolus) using a premixed bag of 4 grams per 100 ml. Infuse the bolus dose over a 20- to 30-minute period. Label the magnesium sulfate line with appropriate medication sticker. Do not infuse other medication into the magnesium sulfate line.

How long do you infuse magnesium sulfate?

The aim should be to maintain serum magnesium concentrations above 0.4 mmol/l. Alternatively, 2-4 ml of Magnesium Sulfate 50% w/v solution (4-8 mmol Mg²⁺) can be injected intramuscularly every 6 hours for 24 hours (4 doses in total).

How do you use magnesium sulfate injection?

Intravenous Infusion: 4 g in 250 mL of 5% Dextrose Injection at a rate not exceeding 3 mL per minute. Usual Dose Range: 1 to 40 g daily. Electrolyte Replenisher: Intramuscular 1 to 2 g in 50% solution four times a day until serum magnesium is within normal limits.

How do you dilute IV magnesium?

Magnesium sulfate injection (50%) must be diluted to a concentration of 20% or less prior to IV infusion. Rate of administration should be slow and cautious, to avoid producing hypermagnesemia. The 50% solution also should be diluted to 20% or less for IM injection in infants and children.

When do you stop magnesium sulfate infusion?

tendon reflexes are absent or in the presence of renal dysfunction. 6 hourly (or more frequently if signs of oliguria). 8. If deep tendon reflexes are diminished or absent, the infusion must be stopped and a Magnesium level performed.

What are the nursing considerations for a patient on magnesium sulfate?

Nursing Implications:

• Drug Interactions:
• Drug Incompatibilities:
• Check serum magnesium level prior to administration.
• Cardiac monitor should be used on patients receiving MgSO₄ intravenously.
• Have injectable form of calcium gluconate available to reverse paralyzing effects of magnesium sulfate.

What should you assess before giving magnesium sulfate?

Before beginning any infusion of magnesium sulfate, the primary RN will obtain baseline vital signs (temperature, pulse, respirations, blood pressure, and O2 saturation).

Does magnesium sulfate lower blood pressure?

Magnesium sulfate may attenuate blood pressure by decreasing the vascular response to pressor substances.

How fast do you run IV magnesium?

When IV magnesium sulfate is ordered the pharmacy automatically sets the rate to run at 2g per hour unless otherwise specified. Often times the physician will specify for 8g to be infused over eight hours.

How do you calculate magnesium sulfate infusion?

ADMINISTRATION OF LOADING DOSE OF MgSO4 Establish an IV line using normal saline or Ringer’s lactate solution. Using a 20 mL syringe, draw 4 g of MgSO4 50% (8 mL) □ Add 12 mL sterile water or saline to the same syringe to make a 20% solution □ Give this 4g MgSO4 20% solution IV over 5 – 20 minutes.

Is magnesium IV painful?

Results: Pain during i.v. pretreatment with magnesium was 31% as compared to 2% for both the lidocaine and control groups (P < 0.05). Seventy-six percent of patients in the control group had pain during i.v. propofol as compared to 32% and 42% in the magnesium and the lidocaine groups respectively (P < 0.05).