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FAQ: What are vasoactive amines?

n. A substance containing amino groups, such as histamine or serotonin, that acts on the blood vessels to alter their permeability or to cause vasodilation.

What are examples of vasoactive amines?

A molecule released from mast cells, basophils, and platelets that induce contraction of endothelium and smooth muscle (examples: histamine and 5-hydroxytryptamine).

What are vasoactive foods?

Vasoactive amines such as tyramine, serotonin and histamine are well known triggers of migraines in some people. They are present naturally in pineapples, bananas, baked meat, vegetables, red wine, wood-matured white wine, avocados, chocolate, citrus fruits and mature cheese.

What do amines do to the body?

Amines participate in important metabolic and physiological functions in living organisms. Polyamines are essential for cell proliferation, growth, renewal, and metabolism. They are involved in nearly every step of DNA, RNA, and protein synthesis, and regulate the permeability and stability of cellular membranes.

What vasoactive means?

Listen to pronunciation. (VAY-zoh-AK-tiv) Describes something that causes the blood vessels to constrict (get narrower) or dilate (get wider).

What are some vasoactive medications?

Four of the commonly used FDA approved vasoactive medications are norepinephrine, phenylephrine, epinephrine, and vasopressin.

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Are amines bad for you?

Intake of low amount of biogenic amines normally does not have harmful effect on human health. However, when their amount in food is too high and detoxification ability is inhibited or disturbed, biogenic amines could cause problem.

Do amines cause migraines?

Some foods contain substances called amines, which if taken in large quantities can cause symptoms of migraine. Caffeine can also have the same effect. Try avoiding the high amine foods for a month.

What is the difference between intolerance and allergy?

A food allergy occurs when the immune system reacts to a harmless food. Food intolerance occurs when the body has a chemical reaction to eating a particular food or drink.

Are amines and histamines the same?

According to the risk assessment of biogenic amines carried out by the European Food Safety Authority (EFSA) [1], the amine content currently found in foods could be responsible of the triggering of health disorders. Histamine is the biogenic amine most commonly associated with the onset of health complaints.

What are dietary amines?

Amines, as well as glutamates and salicylates, are organic compounds that can act on the human brain and blood vessels. These naturally-occurring components of food have been associated with a variety of symptoms including mental confusion, depression, and migraine headaches.

What are the vasoactive substances?

Vasoactive substances are comprised of a chemically heterogeneous group, proteins, peptides, lipids, and nucleosides, affecting vascular tone and leading to either vasodilation or vasoconstriction.

What are the vasoactive chemicals?

Vasoactive agents include histamine, serotonin, bradykinin, angiotensin II, norepinephrine, platelet activating factor, phospholipase A2, arachidonic acid, prostaglandins, glutamate, leukotrienes, free oxygen radicals, the complement-derived polypeptide Csa-desArg, interleukins 1α, 1β and 2, macrophage inflammatory

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What tissues do vasoactive substances affect?

These vasoactive substances affect local and systemic vascular resistance, vascular permeability, fluid balance, and myocardial con- tractile force and contribute to the “whole body inflam- matory response” associated with CPB [l].

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